A new journal, Unio cum Christo, just published my article, “Erasmus and the Book That Changed the World Five Hundred Years Ago” (Unio cum Christo 2.2 [Oct 2016] 29–48). Erasmus published the first Greek New Testament on March 1, 1516. This article honors him and discusses the impact that his Novum Instrumentum Omne (a book that is almost completely unknown except by biblical scholars) has had on western civilization and the world.